Predicting Antimicrobial Activity at the Target Site: Pharmacokinetic/Pharmacodynamic Indices versus Time–Kill Approaches

Antibiotic dosing strategies are generally based on systemic drug concentrations. However, drug concentrations at the infection site drive antimicrobial effect, and efficacy predictions and dosing strategies should be based on these concentrations. We set out to review different translational pharma...

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Detalles Bibliográficos
Autores principales: van Os, Wisse, Zeitlinger, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698708/
https://www.ncbi.nlm.nih.gov/pubmed/34943697
http://dx.doi.org/10.3390/antibiotics10121485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698708/
https://www.ncbi.nlm.nih.gov/pubmed/34943697
http://dx.doi.org/10.3390/antibiotics10121485

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