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Exploration of the Structure–Function Relationships of a Novel Frog Skin Secretion-Derived Bioactive Peptide, t-DPH1, through Use of Rational Design, Cationicity Enhancement and In Vitro Studies

Amphibian skin-derived antimicrobial peptides (AMPs) have attracted increasing attention from scientists because of their excellent bioactivity and low drug resistance. In addition to being the alternative choice of antibiotics or anticancer agents, natural AMPs can also be modified as templates to...

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Detalles Bibliográficos
Autores principales: Qin, Haixin, Fang, Hantian, Chen, Xiaoling, Wang, Lei, Ma, Chengbang, Xi, Xinping, Chen, Tianbao, Shaw, Chris, Zhou, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698721/
https://www.ncbi.nlm.nih.gov/pubmed/34943741
http://dx.doi.org/10.3390/antibiotics10121529