Pheno-SELEX: Engineering Anti-Metastatic Aptamers through Targeting the Invasive Phenotype Using Systemic Evolution of Ligands by Exponential Enrichment

Multiple methods (e.g., small molecules and antibodies) have been engineered to target specific proteins and signaling pathways in cancer. However, many mediators of the cancer phenotype are unknown and the ability to target these phenotypes would help mitigate cancer. Aptamers are small DNA or RNA...

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Detalles Bibliográficos
Autores principales: Shelley, Greg, Dai, Jinlu, Keller, Jill M., Keller, Evan T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698736/
https://www.ncbi.nlm.nih.gov/pubmed/34940365
http://dx.doi.org/10.3390/bioengineering8120212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698736/
https://www.ncbi.nlm.nih.gov/pubmed/34940365
http://dx.doi.org/10.3390/bioengineering8120212

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