Synergism of a novel MCL-1 downregulator, acriflavine, with navitoclax (ABT-263) in triple-negative breast cancer, lung adenocarcinoma and glioblastoma multiforme

Myeloid cell leukemia sequence 1 (MCL-1), an anti-apoptotic B-cell lymphoma 2 (BCL-2) family molecule frequently amplified in various human cancer cells, is known to be critical for cancer cell survival. MCL-1 has been recognized as a target molecule for cancer treatment. While various agents have e...

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Detalles Bibliográficos
Autores principales: Lee, Anbok, Jin, Hyeon-Ok, Haque, Md. Masudul, Kim, Hee Yeon, Jung, Hana, Park, Jin Hee, Kim, Ilhwan, Song, Joo Yeon, Yoon, Hye Kyoung, Kim, Hyoung Kyu, Han, Jin, Park, In-Chul, Kim, Kwang Seok, Park, Sae Gwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698747/
https://www.ncbi.nlm.nih.gov/pubmed/34913076
http://dx.doi.org/10.3892/ijo.2021.5292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698747/
https://www.ncbi.nlm.nih.gov/pubmed/34913076
http://dx.doi.org/10.3892/ijo.2021.5292

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