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Evaluation of ATOX1 as a Potential Predictive Biomarker for Tetrathiomolybdate Treatment of Breast Cancer Patients with High Risk of Recurrence

Copper plays a key role in cancer metastasis, which is the most common cause of cancer death. Copper depletion treatment with tetrathiomolybdate (TM) improved disease-free survival in breast cancer patients with high risk of recurrence in a phase II clinical trial. Because the copper metallochaperon...

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Detalles Bibliográficos
Autores principales: Blockhuys, Stéphanie, Hildesjö, Camilla, Olsson, Hans, Vahdat, Linda, Wittung-Stafshede, Pernilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698757/
https://www.ncbi.nlm.nih.gov/pubmed/34944703
http://dx.doi.org/10.3390/biomedicines9121887