Deciphering the Role of Pyrvinium Pamoate in the Generation of Integrated Stress Response and Modulation of Mitochondrial Function in Myeloid Leukemia Cells through Transcriptome Analysis

Pyrvinium pamoate, a widely-used anthelmintic agent, reportedly exhibits significant anti-tumor effects in several cancers. However, the efficacy and mechanisms of pyrvinium against myeloid leukemia remain unclear. The growth inhibitory effects of pyrvinium were tested in human AML cell lines. Trans...

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Detalles Bibliográficos
Autores principales: Fu, Yu-Hsuan, Tseng, Chi-Yang, Lu, Jeng-Wei, Lu, Wen-Hui, Lan, Pei-Qi, Chen, Chien-Yuan, Ou, Da-Liang, Lin, Liang-In
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698814/
https://www.ncbi.nlm.nih.gov/pubmed/34944685
http://dx.doi.org/10.3390/biomedicines9121869

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698814/
https://www.ncbi.nlm.nih.gov/pubmed/34944685
http://dx.doi.org/10.3390/biomedicines9121869

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