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CCN2 Aggravates the Immediate Oxidative Stress–DNA Damage Response following Renal Ischemia–Reperfusion Injury

AKI, due to the fact of altered oxygen supply after kidney transplantation, is characterized by renal ischemia–reperfusion injury (IRI). Recent data suggest that AKI to CKD progression may be driven by cellular senescence evolving from prolonged DNA damage response (DDR) following oxidative stress....

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Detalles Bibliográficos
Autores principales: Valentijn, Floris A., Knoppert, Sebastiaan N., Pissas, Georgios, Rodrigues-Diez, Raúl R., Marquez-Exposito, Laura, Broekhuizen, Roel, Mokry, Michal, Kester, Lennart A., Falke, Lucas L., Goldschmeding, Roel, Ruiz-Ortega, Marta, Eleftheriadis, Theodoros, Nguyen, Tri Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698829/
https://www.ncbi.nlm.nih.gov/pubmed/34943123
http://dx.doi.org/10.3390/antiox10122020