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Diosmin Alleviates Doxorubicin-Induced Liver Injury via Modulation of Oxidative Stress-Mediated Hepatic Inflammation and Apoptosis via NfkB and MAPK Pathway: A Preclinical Study

Hepatotoxicity caused by chemotherapeutic drugs (e.g., doxorubicin) is of critical concern in cancer therapy. This study focused on investigating the modulatory effects of diosmin against doxorubicin-induced hepatotoxicity in Male Wistar rats. Male Wistar rats were randomly divided into four groups:...

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Detalles Bibliográficos
Autores principales: AlAsmari, Abdullah F., Alharbi, Metab, Alqahtani, Faleh, Alasmari, Fawaz, AlSwayyed, Mohammed, Alzarea, Sami I., Al-Alallah, Ibrahim A., Alghamdi, Adel, Hakami, Hassan M., Alyousef, Meshal K., Sari, Youssef, Ali, Nemat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698866/
https://www.ncbi.nlm.nih.gov/pubmed/34943101
http://dx.doi.org/10.3390/antiox10121998