TERT Promoter Mutations Increase Sense and Antisense Transcription from the TERT Promoter

Background: Chief among mechanisms of telomerase reverse transcriptase (TERT) reactivation is the appearance of mutations in the TERT promoter. The two main TERT promoter mutations are C>T transitions located −146C>T and −124C>T upstream from the translational start site. They generate a no...

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Detalles Bibliográficos
Autores principales: Hafezi, François, Jaxel, Lisa, Lemaire, Morgane, Turner, Jonathan D., Perez-Bercoff, Danielle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698883/
https://www.ncbi.nlm.nih.gov/pubmed/34944589
http://dx.doi.org/10.3390/biomedicines9121773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698883/
https://www.ncbi.nlm.nih.gov/pubmed/34944589
http://dx.doi.org/10.3390/biomedicines9121773

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