Cargando…
TERT Promoter Mutations Increase Sense and Antisense Transcription from the TERT Promoter
Background: Chief among mechanisms of telomerase reverse transcriptase (TERT) reactivation is the appearance of mutations in the TERT promoter. The two main TERT promoter mutations are C>T transitions located −146C>T and −124C>T upstream from the translational start site. They generate a no...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698883/ https://www.ncbi.nlm.nih.gov/pubmed/34944589 http://dx.doi.org/10.3390/biomedicines9121773 |