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Long-Term Pharmacological Inhibition of the Activity of All NOS Isoforms Rather Than Genetic Knock-Out of Endothelial NOS Leads to Impaired Spatial Learning and Memory in C57BL/6 Mice
Increasing epidemiological and experimental evidence points to a link between arterial stiffness and rapid cognitive decline. However, the underlying mechanism linking the two diseases is still unknown. The importance of nitric oxide synthases in both diseases is well-defined. In this study, we intr...
Autores principales: | Hendrickx, Jhana O., De Moudt, Sofie, Calus, Elke, De Deyn, Peter Paul, Van Dam, Debby, De Meyer, Guido R. Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698888/ https://www.ncbi.nlm.nih.gov/pubmed/34944725 http://dx.doi.org/10.3390/biomedicines9121905 |
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