Preparation and Characterization of Silymarin-Conjugated Gold Nanoparticles with Enhanced Anti-Fibrotic Therapeutic Effects against Hepatic Fibrosis in Rats: Role of MicroRNAs as Molecular Targets

Background: The main obstacles of silymarin (SIL) application in liver diseases are its low bioavailability, elevated metabolism, rapid excretion in bile and urine, and inefficient intestinal resorption. The study aimed to synthesize and characterize silymarin-conjugated gold nanoparticles (SGNPs) f...

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Detalles Bibliográficos
Autores principales: Abdullah, Abdullah Saad, El Sayed, Ibrahim El Tantawy, El-Torgoman, Abdel Moneim A., Alghamdi, Noweir Ahmad, Ullah, Sami, Wageh, S., Kamel, Maher A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698929/
https://www.ncbi.nlm.nih.gov/pubmed/34944582
http://dx.doi.org/10.3390/biomedicines9121767

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8698929/
https://www.ncbi.nlm.nih.gov/pubmed/34944582
http://dx.doi.org/10.3390/biomedicines9121767

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