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Central Nervous System Delivery of Antibodies and Their Single-Domain Antibodies and Variable Fragment Derivatives with Focus on Intranasal Nose to Brain Administration

IgG antibodies are some of the most important biopharmaceutical molecules with a high market volume. In spite of the fact that clinical therapies with antibodies are broadly utilized in oncology, immunology and hematology, their delivery strategies and biodistribution need improvement, their limitat...

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Detalles Bibliográficos
Autores principales: Soleimanizadeh, Arghavan, Dinter, Heiko, Schindowski, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699001/
https://www.ncbi.nlm.nih.gov/pubmed/34939999
http://dx.doi.org/10.3390/antib10040047