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Characterization and Molecular Determinants for β-Lactam Specificity of the Multidrug Efflux Pump AcrD from Salmonella typhimurium

Gram-negative Tripartite Resistance Nodulation and cell Division (RND) superfamily efflux pumps confer various functions, including multidrug and bile salt resistance, quorum-sensing, virulence and can influence the rate of mutations on the chromosome. Multidrug RND efflux systems are often characte...

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Detalles Bibliográficos
Autores principales: Cuesta Bernal, Jenifer, El-Delik, Jasmin, Göttig, Stephan, Pos, Klaas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699017/
https://www.ncbi.nlm.nih.gov/pubmed/34943706
http://dx.doi.org/10.3390/antibiotics10121494