A Novel Peptide-MHC Targeted Chimeric Antigen Receptor T Cell Forms a T Cell-like Immune Synapse

Chimeric Antigen Receptor (CAR) T cell therapy is a promising form of adoptive cell therapy that re-engineers patient-derived T cells to express a hybrid receptor specific to a tumour-specific antigen of choice. Many well-characterised tumour antigens are intracellular and therefore not accessible t...

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Detalles Bibliográficos
Autores principales: Wang, Stacie Shiqi, Luong, Kylie, Gracey, Fiona Margaret, Jabar, Shereen, McColl, Brad, Cross, Ryan Stanley, Jenkins, Misty Rayna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699022/
https://www.ncbi.nlm.nih.gov/pubmed/34944696
http://dx.doi.org/10.3390/biomedicines9121875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699022/
https://www.ncbi.nlm.nih.gov/pubmed/34944696
http://dx.doi.org/10.3390/biomedicines9121875

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