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A Novel Peptide-MHC Targeted Chimeric Antigen Receptor T Cell Forms a T Cell-like Immune Synapse
Chimeric Antigen Receptor (CAR) T cell therapy is a promising form of adoptive cell therapy that re-engineers patient-derived T cells to express a hybrid receptor specific to a tumour-specific antigen of choice. Many well-characterised tumour antigens are intracellular and therefore not accessible t...
Autores principales: | Wang, Stacie Shiqi, Luong, Kylie, Gracey, Fiona Margaret, Jabar, Shereen, McColl, Brad, Cross, Ryan Stanley, Jenkins, Misty Rayna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699022/ https://www.ncbi.nlm.nih.gov/pubmed/34944696 http://dx.doi.org/10.3390/biomedicines9121875 |
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