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In Silico Drug Repurposing for Anti-Inflammatory Therapy: Virtual Search for Dual Inhibitors of Caspase-1 and TNF-Alpha

Inflammation involves a complex biological response of the body tissues to damaging stimuli. When dysregulated, inflammation led by biomolecular mediators such as caspase-1 and tumor necrosis factor-alpha (TNF-alpha) can play a detrimental role in the progression of different medical conditions such...

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Detalles Bibliográficos
Autores principales: Speck-Planche, Alejandro, Kleandrova, Valeria V., Scotti, Marcus T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699067/
https://www.ncbi.nlm.nih.gov/pubmed/34944476
http://dx.doi.org/10.3390/biom11121832