Differential Regulation of the EGFR/PI3K/AKT/PTEN Pathway between Low- and High-Grade Gliomas

Gliomas represent 70% of all central system nervous tumors and are classified according to the degree of malignancy as low- or high-grade. The permanent activation of the EGFR/PI3K/AKT pathway by various genetic or post-translational alterations of EGFR, PI3KCA, and PTEN has been associated with inc...

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Detalles Bibliográficos
Autores principales: Erira, Alveiro, Velandia, Fernando, Penagos, José, Zubieta, Camilo, Arboleda, Gonzalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699139/
https://www.ncbi.nlm.nih.gov/pubmed/34942957
http://dx.doi.org/10.3390/brainsci11121655

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699139/
https://www.ncbi.nlm.nih.gov/pubmed/34942957
http://dx.doi.org/10.3390/brainsci11121655

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