Cargando…

Differential Regulation of the EGFR/PI3K/AKT/PTEN Pathway between Low- and High-Grade Gliomas

Gliomas represent 70% of all central system nervous tumors and are classified according to the degree of malignancy as low- or high-grade. The permanent activation of the EGFR/PI3K/AKT pathway by various genetic or post-translational alterations of EGFR, PI3KCA, and PTEN has been associated with inc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Erira, Alveiro, Velandia, Fernando, Penagos, José, Zubieta, Camilo, Arboleda, Gonzalo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699139/ https://www.ncbi.nlm.nih.gov/pubmed/34942957 http://dx.doi.org/10.3390/brainsci11121655

Ejemplares similares

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice
por: Sun, Chen, et al.
Publicado: (2014)

Human papillomavirus, Epstein–Barr virus, and Candida albicans co‐infection in oral leukoplakia with different degrees of dysplasia
por: Erira, Alveiro T, et al.
Publicado: (2021)

Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention
por: Davis, Nicole M., et al.
Publicado: (2014)

SALL4 suppresses PTEN expression to promote glioma cell proliferation via PI3K/AKT signaling pathway
por: Liu, Chuanjin, et al.
Publicado: (2017)

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models
por: Carnero, Amancio, et al.
Publicado: (2014)

Dysregulation of PI3K/Akt/PTEN Pathway in Canine Mammary Tumor
por: Kim, Soo-Hyeon, et al.
Publicado: (2021)

PI3K/AKT/PTEN Signaling as a Molecular Target in Leukemia Angiogenesis
por: Okumura, Naoko, et al.
Publicado: (2012)

Roles of PI3K/AKT/PTEN Pathway as a Target for Pharmaceutical Therapy
por: Matsuda, Satoru, et al.
Publicado: (2013)

PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis
por: Lee, Min-Sik, et al.
Publicado: (2015)

Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway
por: Dasari, Venkata Ramesh, et al.
Publicado: (2010)

Promoter methylation of PTEN gene in high grade gliomas
por: Lavanya, C, et al.
Publicado: (2014)

Retraction: Upregulation of PTEN in Glioma Cells by Cord Blood Mesenchymal Stem Cells Inhibits Migration via Downregulation of the PI3K/Akt Pathway
Publicado: (2020)

Increased signalling of EGFR and IGF1R, and deregulation of PTEN/PI3K/Akt pathway are related with trastuzumab resistance in HER2 breast carcinomas
por: Gallardo, A, et al.
Publicado: (2012)

MicroRNA-1231 exerts a tumor suppressor role through regulating the EGFR/PI3K/AKT axis in glioma
por: Zhang, Jiale, et al.
Publicado: (2018)

Antiglioma effects of cytarabine on leptomeningeal metastasis of high-grade glioma by targeting the PI3K/Akt/mTOR pathway
por: Zhao, Kai-Hong, et al.
Publicado: (2017)

The PTEN–PI3K Axis in Cancer
por: Papa, Antonella, et al.
Publicado: (2019)

miR-23b-3p regulates differentiation of osteoclasts by targeting PTEN via the PI3k/AKT pathway
por: Chai, Jiwei, et al.
Publicado: (2019)

Roles for PI3K/AKT/PTEN Pathway in Cell Signaling of Nonalcoholic Fatty Liver Disease
por: Matsuda, Satoru, et al.
Publicado: (2013)

Implications of PI3K/AKT/PTEN Signaling on Superoxide Dismutases Expression and in the Pathogenesis of Alzheimer’s Disease
por: Matsuda, Satoru, et al.
Publicado: (2018)

Physiological levels of the PTEN-PI3K-AKT axis activity are required for maintenance of Burkitt lymphoma
por: Gehringer, Franziska, et al.
Publicado: (2019)

Author Correction: PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis
por: Lee, Min-Sik, et al.
Publicado: (2020)

YB-1 Oncoprotein Controls PI3K/Akt Pathway by Reducing Pten Protein Level
por: Delicato, Antonella, et al.
Publicado: (2021)

The PI3K/AKT Pathway and PTEN Gene Are Involved in “Tree-Top Disease” of Lymantria dispar
por: Li, Fengjiao, et al.
Publicado: (2022)

Research Progress of PI3K/PTEN/AKT Signaling Pathway Associated with Renal Cell Carcinoma
por: Fang, Yakun, et al.
Publicado: (2022)

lncNALT knockdown ameliorates hypertensive retinopathy via PTEN/PI3K/AKT pathway
por: Kang, Haijun, et al.
Publicado: (2023)

A Drosophila Model for EGFR-Ras and PI3K-Dependent Human Glioma
por: Read, Renee D., et al.
Publicado: (2009)

Mutation in the PTEN/MMAC1 gene in archival low grade and high grade gliomas
por: Davies, M P A, et al.
Publicado: (1999)

Targeting EGFR/PI3K/AKT/mTOR Signaling in Hepatocellular Carcinoma
por: Bang, Jieun, et al.
Publicado: (2023)

Columbamine-Mediated PTEN/AKT Signal Pathway Regulates the Progression of Glioma
por: Niu, Hai-Tao, et al.
Publicado: (2021)

RAS/RAF/MEK/ERK and PI3K/PTEN/AKT Signaling in Malignant Melanoma Progression and Therapy
por: Yajima, Ichiro, et al.
Publicado: (2012)

A caveolin-dependent and PI3K/AKT-independent role of PTEN in β-catenin transcriptional activity
por: Conde-Perez, Alejandro, et al.
Publicado: (2015)

PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis
por: Xu, Wenting, et al.
Publicado: (2018)

JQ1 suppresses tumor growth via PTEN/PI3K/AKT pathway in endometrial cancer
por: Qiu, Haifeng, et al.
Publicado: (2016)

Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT
por: Zheng, Zhiming, et al.
Publicado: (2017)

Association of polymorphisms of PTEN, AKT1, PI3K, AR, and AMACR genes in patients with prostate cancer
por: de Nóbrega, Monyse, et al.
Publicado: (2020)

Critical implication of the PTEN/PI3K/AKT pathway during BMP2-induced heterotopic ossification
por: Dong, Jun, et al.
Publicado: (2021)

Upregulation of NFKBIZ affects bladder cancer progression via the PTEN/PI3K/Akt signaling pathway
por: Xu, Tao, et al.
Publicado: (2021)

MiRNA-132 regulates the development of osteoarthritis in correlation with the modulation of PTEN/PI3K/AKT signaling
por: Zhang, Wei, et al.
Publicado: (2021)

Regulation of the PTEN/PI3K/AKT pathway in RCC using the active compounds of natural products in vitro
por: Wang, Xue, et al.
Publicado: (2021)

PTEN/PI3K/Akt pathway alters sensitivity of T-cell acute lymphoblastic leukemia to l-asparaginase
por: Hlozkova, Katerina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8qm2sb631jcue4ftiqa28bo737