Ribociclib Induces Broad Chemotherapy Resistance and EGFR Dependency in ESR1 Wildtype and Mutant Breast Cancer

SIMPLE SUMMARY: Disease progression while receiving treatment is a major problem in breast cancer. Mutations in the oestrogen receptor-α often lead to loss of drug activity, resulting in an inability of anti-oestrogens to stop cancer growth. There is an urgent need to establish which therapies can e...

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Detalles Bibliográficos
Autores principales: Mayayo-Peralta, Isabel, Faggion, Beatrice, Hoekman, Liesbeth, Morris, Ben, Lieftink, Cor, Goldsbrough, Isabella, Buluwela, Lakjaya, Siefert, Joseph C., Post, Harm, Altelaar, Maarten, Beijersbergen, Roderick, Ali, Simak, Zwart, Wilbert, Prekovic, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699146/
https://www.ncbi.nlm.nih.gov/pubmed/34944934
http://dx.doi.org/10.3390/cancers13246314

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699146/
https://www.ncbi.nlm.nih.gov/pubmed/34944934
http://dx.doi.org/10.3390/cancers13246314

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