Signal Enhancement in Oriented Immunosorbent Assays: A Balance between Accessibility of Antigen Binding Sites and Avidity

The sensitivity of immunoassays was reported to be increased by the orientation of antibodies. We investigated how the size and valence of antigens and orientation and valence of antibodies contribute to the analytical sensitivity of ELISA. Antigens differing in size and number of epitopes were comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Susini, Vanessa, Fierabracci, Vanna, Barria, Gaia, Dodoli, Lisa, Caponi, Laura, Paolicchi, Aldo, Franzini, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699147/
https://www.ncbi.nlm.nih.gov/pubmed/34940250
http://dx.doi.org/10.3390/bios11120493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699147/
https://www.ncbi.nlm.nih.gov/pubmed/34940250
http://dx.doi.org/10.3390/bios11120493

Ejemplares similares