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Physiological and Pathophysiological Roles of Mitochondrial Na(+)-Ca(2+) Exchanger, NCLX, in Hearts

It has been over 10 years since SLC24A6/SLC8B1, coding the Na(+)/Ca(2+)/Li(+) exchanger (NCLX), was identified as the gene responsible for mitochondrial Na(+)-Ca(2+) exchange, a major Ca(2+) efflux system in cardiac mitochondria. This molecular identification enabled us to determine structure–functi...

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Detalles Bibliográficos
Autores principales: Takeuchi, Ayako, Matsuoka, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699148/
https://www.ncbi.nlm.nih.gov/pubmed/34944520
http://dx.doi.org/10.3390/biom11121876