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Loss of SATB2 Occurs More Frequently Than CDX2 Loss in Colorectal Carcinoma and Identifies Particularly Aggressive Cancers in High-Risk Subgroups

SIMPLE SUMMARY: The immunohistochemical analysis of Special AT-rich sequence-binding protein 2 (SATB2) is increasingly being used to detect colorectal differentiation. Our study aimed to investigate SATB2 expression levels and the prognostic relevance of SATB2 loss in colorectal carcinoma (CRC), esp...

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Detalles Bibliográficos
Autores principales: Schmitt, Maxime, Silva, Miguel, Konukiewitz, Björn, Lang, Corinna, Steiger, Katja, Halfter, Kathrin, Engel, Jutta, Jank, Paul, Pfarr, Nicole, Wilhelm, Dirk, Foersch, Sebastian, Denkert, Carsten, Tschurtschenthaler, Markus, Weichert, Wilko, Jesinghaus, Moritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699173/
https://www.ncbi.nlm.nih.gov/pubmed/34944797
http://dx.doi.org/10.3390/cancers13246177