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Cell Type-Specific Role of RNA Nuclease SMG6 in Neurogenesis

SMG6 is an endonuclease, which cleaves mRNAs during nonsense-mediated mRNA decay (NMD), thereby regulating gene expression and controling mRNA quality. SMG6 has been shown as a differentiation license factor of totipotent embryonic stem cells. To investigate whether it controls the differentiation o...

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Detalles Bibliográficos
Autores principales: Guerra, Gabriela Maria, May, Doreen, Kroll, Torsten, Koch, Philipp, Groth, Marco, Wang, Zhao-Qi, Li, Tang-Liang, Grigaravičius, Paulius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699217/
https://www.ncbi.nlm.nih.gov/pubmed/34943873
http://dx.doi.org/10.3390/cells10123365