The Autophagy Inhibitor Chloroquine, Alone or in Combination with mTOR Inhibitors, Displays Anti-Tumor Effects in In Vitro and In Vivo Lung Carcinoid Models

SIMPLE SUMMARY: Neuroendocrine neoplasms of the lung (lung carcinoids) are often diagnosed when they are not surgically curable, and treatment options are limited. One of the approved options for treating inoperable tumors is everolimus, an mTOR inhibitor. Activation of mTOR inhibits autophagy, whic...

Descripción completa

Detalles Bibliográficos
Autores principales: Knigin, Adi, Avniel-Polak, Shani, Leibowitz, Gil, Oleinikov, Kira, Gross, David J., Grozinsky-Glasberg, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699234/
https://www.ncbi.nlm.nih.gov/pubmed/34944946
http://dx.doi.org/10.3390/cancers13246327

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699234/
https://www.ncbi.nlm.nih.gov/pubmed/34944946
http://dx.doi.org/10.3390/cancers13246327

Ejemplares similares