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Developing a Nationwide Infrastructure for Therapeutic Drug Monitoring of Targeted Oral Anticancer Drugs: The ON-TARGET Study Protocol

SIMPLE SUMMARY: Relationships between drug concentrations in blood and efficacy and/or toxicity have been reported for up to 80% of oral anticancer drugs (OADs). Most OADs exhibit highly variable drug concentrations at the approved dose. This may result in a significant proportion of patients with s...

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Detalles Bibliográficos
Autores principales: Mc Laughlin, Anna M., Schmulenson, Eduard, Teplytska, Olga, Zimmermann, Sebastian, Opitz, Patrick, Groenland, Stefanie L., Huitema, Alwin D. R., Steeghs, Neeltje, Müller, Lothar, Fuxius, Stefan, Illerhaus, Gerald, Joerger, Markus, Mayer, Frank, Fuhr, Uwe, Holdenrieder, Stefan, Hempel, Georg, Scherf-Clavel, Oliver, Jaehde, Ulrich, Kloft, Charlotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699239/
https://www.ncbi.nlm.nih.gov/pubmed/34944899
http://dx.doi.org/10.3390/cancers13246281