Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid

The low bioavailability of oral drugs due to first pass metabolism is a major obstacle in drug development. With significant developments in the field of in vitro organ modeling and microfluidic chip three-dimensional (3D) printing, the challenge is to apply these for the production and evaluation o...

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Detalles Bibliográficos
Autores principales: Lee, Bo-Eun, Kim, Do-Kyung, Lee, Hyunil, Yoon, Siyeong, Park, Sin-Hyung, Lee, Soonchul, Yoo, Jongman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699265/
https://www.ncbi.nlm.nih.gov/pubmed/34943808
http://dx.doi.org/10.3390/cells10123301

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699265/
https://www.ncbi.nlm.nih.gov/pubmed/34943808
http://dx.doi.org/10.3390/cells10123301

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