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Recapitulation of First Pass Metabolism Using 3D Printed Microfluidic Chip and Organoid
The low bioavailability of oral drugs due to first pass metabolism is a major obstacle in drug development. With significant developments in the field of in vitro organ modeling and microfluidic chip three-dimensional (3D) printing, the challenge is to apply these for the production and evaluation o...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699265/ https://www.ncbi.nlm.nih.gov/pubmed/34943808 http://dx.doi.org/10.3390/cells10123301 |