Pathophysiological Mechanisms in Neurodevelopmental Disorders Caused by Rac GTPases Dysregulation: What’s behind Neuro-RACopathies

Rho family guanosine triphosphatases (GTPases) regulate cellular signaling and cytoskeletal dynamics, playing a pivotal role in cell adhesion, migration, and cell cycle progression. The Rac subfamily of Rho GTPases consists of three highly homologous proteins, Rac 1–3. The proper function of Rac1 an...

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Detalles Bibliográficos
Autores principales: Scala, Marcello, Nishikawa, Masashi, Nagata, Koh-ichi, Striano, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699292/
https://www.ncbi.nlm.nih.gov/pubmed/34943902
http://dx.doi.org/10.3390/cells10123395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699292/
https://www.ncbi.nlm.nih.gov/pubmed/34943902
http://dx.doi.org/10.3390/cells10123395

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