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Impact of a Faulty Germinal Center Reaction on the Pathogenesis of Primary Diffuse Large B Cell Lymphoma of the Central Nervous System

SIMPLE SUMMARY: The pathogenetic mechanisms and peculiar tropism of primary CNS lymphoma (PCNSL) of the central nervous system (CNS) have been the subject of debate for decades. Hypothesis-driven targeted molecular studies have revealed that PCNSLs derived from self-/polyreactive B cells that have e...

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Detalles Bibliográficos
Autores principales: Montesinos-Rongen, Manuel, Brunn, Anna, Sanchez-Ruiz, Monica, Küppers, Ralf, Siebert, Reiner, Deckert, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699297/
https://www.ncbi.nlm.nih.gov/pubmed/34944954
http://dx.doi.org/10.3390/cancers13246334