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RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth

Diacylglycerol kinase β (DGKβ) is an enzyme that converts diacylglycerol to phosphatidic acid and is mainly expressed in the cerebral cortex, hippocampus and striatum. We previously reported that DGKβ induces neurite outgrowth and spinogenesis, contributing to higher brain functions, including emoti...

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Detalles Bibliográficos
Autores principales: Kano, Takuya, Tsumagari, Ryosuke, Nakashima, Akio, Kikkawa, Ushio, Ueda, Shuji, Yamanoue, Minoru, Takei, Nobuyuki, Shirai, Yasuhito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699322/
https://www.ncbi.nlm.nih.gov/pubmed/34944458
http://dx.doi.org/10.3390/biom11121814