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RalA, PLD and mTORC1 Are Required for Kinase-Independent Pathways in DGKβ-Induced Neurite Outgrowth
Diacylglycerol kinase β (DGKβ) is an enzyme that converts diacylglycerol to phosphatidic acid and is mainly expressed in the cerebral cortex, hippocampus and striatum. We previously reported that DGKβ induces neurite outgrowth and spinogenesis, contributing to higher brain functions, including emoti...
Autores principales: | Kano, Takuya, Tsumagari, Ryosuke, Nakashima, Akio, Kikkawa, Ushio, Ueda, Shuji, Yamanoue, Minoru, Takei, Nobuyuki, Shirai, Yasuhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699322/ https://www.ncbi.nlm.nih.gov/pubmed/34944458 http://dx.doi.org/10.3390/biom11121814 |
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