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A Computational Approach to Investigate TDP-43 RNA-Recognition Motif 2 C-Terminal Fragments Aggregation in Amyotrophic Lateral Sclerosis

Many of the molecular mechanisms underlying the pathological aggregation of proteins observed in neurodegenerative diseases are still not fully understood. Among the aggregate-associated diseases, Amyotrophic Lateral Sclerosis (ALS) is of relevant importance. In fact, although understanding the proc...

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Detalles Bibliográficos
Autores principales: Grassmann, Greta, Miotto, Mattia, Di Rienzo, Lorenzo, Salaris, Federico, Silvestri, Beatrice, Zacco, Elsa, Rosa, Alessandro, Tartaglia, Gian Gaetano, Ruocco, Giancarlo, Milanetti, Edoardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699346/
https://www.ncbi.nlm.nih.gov/pubmed/34944548
http://dx.doi.org/10.3390/biom11121905