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A Computational Approach to Investigate TDP-43 RNA-Recognition Motif 2 C-Terminal Fragments Aggregation in Amyotrophic Lateral Sclerosis
Many of the molecular mechanisms underlying the pathological aggregation of proteins observed in neurodegenerative diseases are still not fully understood. Among the aggregate-associated diseases, Amyotrophic Lateral Sclerosis (ALS) is of relevant importance. In fact, although understanding the proc...
Autores principales: | Grassmann, Greta, Miotto, Mattia, Di Rienzo, Lorenzo, Salaris, Federico, Silvestri, Beatrice, Zacco, Elsa, Rosa, Alessandro, Tartaglia, Gian Gaetano, Ruocco, Giancarlo, Milanetti, Edoardo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699346/ https://www.ncbi.nlm.nih.gov/pubmed/34944548 http://dx.doi.org/10.3390/biom11121905 |
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