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Genetic and Epigenetic Targeting Therapy for Pediatric Acute Lymphoblastic Leukemia
Acute lymphoblastic leukemia is the most common malignancy in children and is characterized by numerous genetic and epigenetic abnormalities. Epigenetic mechanisms, including DNA methylations and histone modifications, result in the heritable silencing of genes without a change in their coding seque...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699354/ https://www.ncbi.nlm.nih.gov/pubmed/34943855 http://dx.doi.org/10.3390/cells10123349 |