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Genetic and Epigenetic Targeting Therapy for Pediatric Acute Lymphoblastic Leukemia

Acute lymphoblastic leukemia is the most common malignancy in children and is characterized by numerous genetic and epigenetic abnormalities. Epigenetic mechanisms, including DNA methylations and histone modifications, result in the heritable silencing of genes without a change in their coding seque...

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Detalles Bibliográficos
Autores principales:	Xu, Huan, Yu, Hui, Jin, Runming, Wu, Xiaoyan, Chen, Hongbo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699354/ https://www.ncbi.nlm.nih.gov/pubmed/34943855 http://dx.doi.org/10.3390/cells10123349

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