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Epithelial-to-Mesenchymal Transition Mediates Resistance to Maintenance Therapy with Vinflunine in Advanced Urothelial Cell Carcinoma

SIMPLE SUMMARY: Platinum-based chemotherapy is the first-line treatment for advanced urothelial cell carcinoma (aUCC). After first-line treatment, we previously showed that maintenance therapy with vinflunine improves progression-free survival. However, some patients are resistant to vinflunine and...

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Detalles Bibliográficos
Autores principales: Font, Albert, Ruiz de Porras, Vicenç, Valderrama, Begoña P., Ramirez, Jose Luis, Nonell, Lara, Virizuela, José Antonio, Anido, Urbano, González-del-Alba, Aránzazu, Lainez, Nuria, Llorente, Maria del Mar, Jiménez, Natalia, Mellado, Begoña, García-Donas, Jesus, Bellmunt, Joaquim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699401/
https://www.ncbi.nlm.nih.gov/pubmed/34944855
http://dx.doi.org/10.3390/cancers13246235