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The Leukemic Phase of ALK-Negative Anaplastic Large Cell Lymphoma Is Associated with CD7 Positivity, Complex Karyotype, TP53 Deletion, and a Poor Prognosis

SIMPLE SUMMARY: Anaplastic large cell lymphoma (ALCL) is a systemic peripheral T-cell neoplasm characterized by strong and uniform CD30 expression and, usually, the aberrant loss of one or more T-cell antigens. ALCL is further classified into anaplastic lymphoma kinase (ALK)-positive and ALK-negativ...

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Detalles Bibliográficos
Autores principales: Qiu, Lianqun, Medeiros, L. Jeffrey, Tang, Guilin, Khanlari, Mahsa, Li, Shaoying, Konoplev, Sergej, Wang, Sa A., Yin, C. Cameron, Khoury, Joseph D., Wang, Wei, Miranda, Roberto N., Iyer, Swaminathan, You, M. James, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699426/
https://www.ncbi.nlm.nih.gov/pubmed/34944936
http://dx.doi.org/10.3390/cancers13246316