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Cyclic Tetra-Adenylate (cA(4)) Recognition by Csa3; Implications for an Integrated Class 1 CRISPR-Cas Immune Response in Saccharolobus solfataricus

Csa3 family transcription factors are ancillary CRISPR-associated proteins composed of N-terminal CARF domains and C-terminal winged helix-turn-helix domains. The activity of Csa3 transcription factors is thought to be controlled by cyclic oligoadenyate (cOA) second messengers produced by type III C...

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Detalles Bibliográficos
Autores principales: Charbonneau, Alexander A., Eckert, Debra M., Gauvin, Colin C., Lintner, Nathanael G., Lawrence, C. Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699464/
https://www.ncbi.nlm.nih.gov/pubmed/34944496
http://dx.doi.org/10.3390/biom11121852