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(−)-Epigallocatechin-3-Gallate Diminishes Intra-and Extracellular Amyloid-Induced Cytotoxic Effects on Cholinergic-like Neurons from Familial Alzheimer’s Disease PSEN1 E280A

Alzheimer’s disease (AD) is a complex neurodegenerative disease characterized by functional disruption, death of cholinergic neurons (ChNs) because of intracellular and extracellular Aβ aggregates, and hyperphosphorylation of protein TAU (p-TAU). To date, there are no efficient therapies against AD....

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Detalles Bibliográficos
Autores principales: Soto-Mercado, Viviana, Mendivil-Perez, Miguel, Velez-Pardo, Carlos, Jimenez-Del-Rio, Marlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699501/
https://www.ncbi.nlm.nih.gov/pubmed/34944489
http://dx.doi.org/10.3390/biom11121845