Bispecific Antibodies for IFN-β Delivery to ErbB2(+) Tumors

The main aim of our work was to create a full-length bispecific antibody (BsAb) as a vehicle for the targeted delivery of interferon-beta (IFN-β) to ErbB2(+) tumor cells in the form of non-covalent complex of BsAb and IFN-β. Such a construct is a CrossMab-type BsAb, consisting of an ErbB2-recognizin...

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Detalles Bibliográficos
Autores principales: Rybchenko, Vladislav S., Panina, Anna A., Aliev, Teimur K., Solopova, Olga N., Balabashin, Dmitry S., Novoseletsky, Valery N., Dolgikh, Dmitry A., Sveshnikov, Petr G., Kirpichnikov, Mikhail P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699518/
https://www.ncbi.nlm.nih.gov/pubmed/34944558
http://dx.doi.org/10.3390/biom11121915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699518/
https://www.ncbi.nlm.nih.gov/pubmed/34944558
http://dx.doi.org/10.3390/biom11121915

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