Transcription Regulation and Genome Rewiring Governing Sensitivity and Resistance to FOXM1 Inhibition in Breast Cancer

SIMPLE SUMMARY: The oncogenic transcription factor FOXM1 is overexpressed in many cancers and associated with poor patient outcomes. Hence, there is much interest in blocking FOXM1 activity in cancer. We used small molecule inhibitors of FOXM1 to understand how they impact gene regulatory networks i...

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Detalles Bibliográficos
Autores principales: Ziegler, Yvonne, Guillen, Valeria Sanabria, Kim, Sung Hoon, Katzenellenbogen, John A., Katzenellenbogen, Benita S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699539/
https://www.ncbi.nlm.nih.gov/pubmed/34944900
http://dx.doi.org/10.3390/cancers13246282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699539/
https://www.ncbi.nlm.nih.gov/pubmed/34944900
http://dx.doi.org/10.3390/cancers13246282

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