Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation

High mobility group box 1 protein (HMGB1), a highly conserved nuclear DNA-binding protein, is a “damage-associated molecular pattern” molecule (DAMP) implicated in both stimulating and inhibiting innate immunity. As reviewed here, HMGB1 is an oxidation-reduction sensitive DAMP bearing three cysteine...

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Detalles Bibliográficos
Autores principales: Andersson, Ulf, Tracey, Kevin J., Yang, Huan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699546/
https://www.ncbi.nlm.nih.gov/pubmed/34943830
http://dx.doi.org/10.3390/cells10123323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699546/
https://www.ncbi.nlm.nih.gov/pubmed/34943830
http://dx.doi.org/10.3390/cells10123323

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