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Genome-Wide DNA Methylation Signatures Predict the Early Asymptomatic Doxorubicin-Induced Cardiotoxicity in Breast Cancer

SIMPLE SUMMARY: This study examined whether the DNA methylation state of peripheral blood mononuclear cells (PBMCs) could predict cardiotoxicity caused by doxorubicin (DOX)-based chemotherapy in breast cancer patients. The results showed a significant difference in the pattern of DNA methylation of...

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Detalles Bibliográficos
Autores principales: Bauer, Michael A., Todorova, Valentina K., Stone, Annjanette, Carter, Weleetka, Plotkin, Matthew D., Hsu, Ping-Ching, Wei, Jeanne Y., Su, Joseph L., Makhoul, Issam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699582/
https://www.ncbi.nlm.nih.gov/pubmed/34944912
http://dx.doi.org/10.3390/cancers13246291