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Current Limitations and Perspectives of Chimeric Antigen Receptor-T-Cells in Acute Myeloid Leukemia

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is the most frequent type of acute leukemia in adults. Allogeneic hematopoietic cell transplantation (allo-HCT) has been the only potentially curative treatment for the majority of patients. The ability of chimeric antigen receptor (CAR)-modified T-cell t...

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Detalles Bibliográficos
Autores principales: Maucher, Marius, Srour, Micha, Danhof, Sophia, Einsele, Hermann, Hudecek, Michael, Yakoub-Agha, Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699597/
https://www.ncbi.nlm.nih.gov/pubmed/34944782
http://dx.doi.org/10.3390/cancers13246157