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Direct visualization by FRET-FLIM of a putative mechanosome complex involving Src, Pyk2 and MBD2 in living MLO-Y4 cells

Earlier, we proposed the “mechanosome” concept as a testable model for understanding how mechanical stimuli detected by cell surface adhesion molecules are transmitted to modulate gene expression inside cells. Here, for the first time we document a putative mechanosome involving Src, Pyk2 and MBD2 i...

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Detalles Bibliográficos
Autores principales: Day, Richard N., Day, Kathleen H., Pavalko, Fredrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699642/
https://www.ncbi.nlm.nih.gov/pubmed/34941939
http://dx.doi.org/10.1371/journal.pone.0261660