Lipotoxicity and β-Cell Failure in Type 2 Diabetes: Oxidative Stress Linked to NADPH Oxidase and ER Stress

A high caloric intake, rich in saturated fats, greatly contributes to the development of obesity, which is the leading risk factor for type 2 diabetes (T2D). A persistent caloric surplus increases plasma levels of fatty acids (FAs), especially saturated ones, which were shown to negatively impact pa...

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Detalles Bibliográficos
Autores principales: Vilas-Boas, Eloisa Aparecida, Almeida, Davidson Correa, Roma, Leticia Prates, Ortis, Fernanda, Carpinelli, Angelo Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699655/
https://www.ncbi.nlm.nih.gov/pubmed/34943836
http://dx.doi.org/10.3390/cells10123328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699655/
https://www.ncbi.nlm.nih.gov/pubmed/34943836
http://dx.doi.org/10.3390/cells10123328

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