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Cancer Therapy Targeting CD47/SIRPα

SIMPLE SUMMARY: The interaction between cluster of differentiation 47 (CD47) on cancer cells and signal regulatory protein alpha (SIRPα) on immune cells, such as macrophages and dendritic cells, generates a “don’t eat me” signal. This is a common mechanism that provides cancer cells an escape from t...

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Detalles Bibliográficos
Autores principales: Dizman, Nazli, Buchbinder, Elizabeth I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699673/
https://www.ncbi.nlm.nih.gov/pubmed/34944850
http://dx.doi.org/10.3390/cancers13246229