YAP1 Is a Potential Predictive Molecular Biomarker for Response to SMO Inhibitor in Medulloblastoma Cells

SIMPLE SUMMARY: Medulloblastoma (MB) is the most common malignant brain tumor in childhood. Currently, MB is assigned in four molecular subgroups (SHH, WNT, Group 3, and Group 4) and subtyped in 12 variants. The alpha subtype of the SHH subgroup bears TP53 mutation and is considered very high risk b...

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Detalles Bibliográficos
Autores principales: Alencastro Veiga Cruzeiro, Gustavo, de Almeida Magalhães, Taciani, Ribeiro de Sousa, Graziella, Bonfim Silva, Ricardo, Alberto Oliveira de Biagi Junior, Carlos, Ferreira das Chagas, Pablo, Gomes de Paula Queiroz, Rosane, Alberto Scrideli, Carlos, Gonzaga Tone, Luiz, Terci Valera, Elvis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699675/
https://www.ncbi.nlm.nih.gov/pubmed/34944872
http://dx.doi.org/10.3390/cancers13246249

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699675/
https://www.ncbi.nlm.nih.gov/pubmed/34944872
http://dx.doi.org/10.3390/cancers13246249

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