Neuroprotective Effect of Clobenpropit against Lipopolysaccharide-Induced Cognitive Deficits via Attenuating Neuroinflammation and Enhancing Mitochondrial Functions in Mice

Clobenpropit (CLO), an antagonist on histamine H(3) receptors (HH3R), has been shown to protect NMDA-induced neuronal necrosis in cortical neuronal cell culture from rats. In this work, we explored its potential on lipopolysaccharide (LPS)-induced memory deficits, neuroinflammation, and mitochondria...

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Detalles Bibliográficos
Autores principales: Mani, Vasudevan, Arfeen, Minhajul, Ali, Hussein M., Abdel-Moneim, Abdel-Moneim Hafez, Aldubayan, Maha, Alhowail, Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699680/
https://www.ncbi.nlm.nih.gov/pubmed/34942919
http://dx.doi.org/10.3390/brainsci11121617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8699680/
https://www.ncbi.nlm.nih.gov/pubmed/34942919
http://dx.doi.org/10.3390/brainsci11121617

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